Awarded in 2019
Home Department: Bioengineering
Faculty Advisors: Eric Appel (Materials Science & Engineering) and Bruce Buckingham (Pediatrics - Endocrinology)
Research Title: Supramolecular Designer Excipient for Improved Insulin Formulations
Research Description: In the United States, 1.5 million Americans have Type 1 Diabetes and rely on subcutaneous daily insulin injections or insulin infusion pumps as an insulin replacement therapy. However, insulin alone is not sufficient to restore native metabolic signalling pathways. Caitlin’s project will generate a new combination drug therapy for the treatment of diabetes that more closely mimics the endogenous beta-cell secretion. The interdisciplinary approach of this project will exploit a particular biomaterial to develop novel dual-hormone formulations with the ability to restore native signaling pathways and enable true replacement therapy, transforming diabetes treatment.
WHERE IS SHE NOW?
Caitlin is a post-doctoral fellow at the Brigham and Women's Hospital in the labs of Jeffrey Karp and Yuhan Lee where she works on designing materials for drug delivery.