The Kuo lab studies a group of airway epithelial cells called pulmonary neuroendocrine (NE) cells.  They are normally a rare cell type in the lung with sensory, neurosecretory, and stem cell functions. Some NE cells can be located at branchpoints in highly innervated clusters called neuroepithelial bodies (NEBs), which are abnormal in several pediatric and adult respiratory diseases.  The lab uses single cell genetic approaches to study NE cell development and function.