Bio-X Graduate Student Fellow

Awarded in 2011
Home Department: Mechanical Engineering
Faculty Advisors: Juan Santiago (Mechanical Engineering), Annelise Barron (Bioengineering), and Michael Snyder (Genetics)

Research Title: Single cell fractionation and analysis of nuclear versus cytoplasmic nucleic acids

Research Description: Denitsa is working on developing a novel assay for physico-chemical extraction and isotachophoresis-based purification and quantification of HIV-1 virus from whole blood. This project combines the fields of mechanical engineering, molecular biology, and infectious diseases. HIV/AIDS is one of the most costly diseases since HIV patients require treatment and need to monitor treatment throughout their lifetime. Development of a rapid, sensitive, and selective diagnostics would help reduce these costs, minimize the spread of the infection, and ensure a timely onset of antiretroviral therapy.


Denitsa is founder and CEO of Marble Therapeutics.