Headshot portrait of Ginger Gramson - Bio-X Undergraduate Fellow
2018 Undergraduate Summer Research Program Participant

Home Department: Human Biology
Mentor: Gerald Crabtree, Pathology and Developmental Biology

Photo of USRP student Ginger Gramson in the laboratory, working with a pipetter.Chromatin regulators are mutated in about 50% of all human cancers, but their modes of leading to cancer are poorly understood. Ginger will use CRISPR/Cas9 to tag chromatin regulators with a protein domain that induces the recruitment of complexes to specific genome sites. This will help elucidate the kinetics and mechanisms in which the actions of chromatin regulators can lead to mis-regulation in the state of cancer.