Bio-X SIGF Graduate Student Fellow

Awarded in 2015
Home Department: Chemical Engineering
Faculty Advisors: Zev Bryant (Bioengineering), Andrew Spakowitz (Chemical Engineering), Chaitan Khosla (Chemistry, Chemical Engineering), W. E. Moerner (Chemistry), and Adam de la Zerda (Structural Biology)

Research Title: Development and application of high-resolution multimodal methods for investigating nucleoprotein complex dynamics

Research Description: The DNA double helix is continually bent, stretched, and unwound by protein machines involved in reading, packaging, and editing the genome. Ivan is developing new sensitive methods for monitoring these deformations in individual DNA molecules in real time. This will allow him to elucidate mechanistic details on the dynamic behavior of nucleoprotein complexes. His work may lead to medical advances such as the development of novel antibiotics that target this molecular machinery.


Ivan is a research and development engineer at the Chan Zuckerberg Biohub.