Home Department: undeclared
Mentor: Emmanuel Mignot (Psychiatry & Behavioral Sciences)

“Examining the Relationship between Circadian Cycles and Breast Cancer Progression and Severity”

Normal sleep circadian rhythms are indispensable to human health, and sleep deprivation has established consequences on metabolic disorders, cardiovascular disease, immune dysregulation, and cancers. Jennifer is using previously collected samples to test the dim-light onset melatonin (DLMO) in women with breast cancer and a control group, matching it with the SomaLogic proteomic profile predicting phase. The transformative, aptamer-based technology allows the accurate measurements of 5,000 proteins in 100Œºl of plasma (or urine). Jennifer is working with Dr. Mignot’s team to analyze samples in the lab and uncover important information regarding circadian disruption and breast cancer prevalence and severity.