Awarded in 2009
Home Department: Bioengineering
Faculty Advisors: Charles Taylor (Bioengineering) and Paul Yock (Bioengineering)
Research Title: Three-Dimensional Vessel Wall Microarchitecture and Remodeling in Abdominal Aortic Aneurysms Quantified Using Immunofluorescent Array Tomography
Research Description: Abdominal aortic aneurysms are a life-threatening degenerative disease in which the structural organization and integrity of the blood vessel wall is lost, resulting in vessel dilation and possible rupture. Sanaz’s work, with Professors Charles Taylor and Paul Yock, has enabled the application of a novel, high resolution, three-dimensional imaging technology, Immunofluorescent Array Tomography, to blood vessels for the first time. Her studies qualitatively and quantitatively characterized both the spatial and temporal remodeling of the microarchitecture and cellular response to aneurysm development. These studies provide a new perspective into aneurysm pathology and may help the development of preventative therapies.
Sanaz is the Co-Founder and President of CrownPoint Medical, LLC (CPM) which provides strategic services that accelerate healthcare innovation and commercialization, working at the intersection of R&D and Marketing to help clients understand the product-customer interface and product-market fit. Previously, at Medtronic, Sanaz was an engineering program manager and marketing product manager and led a cross-functional and multi-company team through needs finding, product development, and commercial global launch of two cardiovascular medical device. Sanaz also participated in Medtronic’s Global Innovation Fellowship program, with a project focused on improving diabetes awareness and detection in South Africa.