Awarded in 2015
Home Department: Bioengineering
Faculty Advisors: Stephen Quake (Bioengineering, Applied Physics), Carlos Simon (OB-GYN/Reproductive, Perinatal & Stem Cell Biology Research), and Barry Behr (Obstetrics & Gynecology)
Research Title: Characterizing the human uterus using single cell RNAseq for mechanistic elucidation and clinical tool development
Research Description: A successful cycle of in vitro fertilization and embryo transfer requires both high-grade embryos and receptive endometrium. While more options are becoming clinically available in developing healthier embryos, a reliable quantitative diagnostic metric with sufficient metric resolution and complexity for evaluating endometrial receptive status remains lacking. Wanxin proposes using single-cell RNA-seq and bioinformatics tools to characterize endometrial receptivity with both higher resolution and a less invasive procedure. The deliverable will be a diagnostic platform that is directly translatable into clinics.
WHERE IS SHE NOW?
Wanxin is a staff scientist at Curio Bioscience in Palo Alto, CA.