Bio-X SIGF Graduate Student Fellow

Awarded in 2013
Home Department: Structural Biology, Public Policy (MPP Program)
Faculty Advisors: Wing Wong (Statistics, Biostatistics), Michael Levitt (Structural Biology), Garry Nolan (Microbiology & Immunology), and Chiara Sabatti (Biostatistics and Statistics)

Research Title: Characterizing single stem cells and their perturbed statesand DNA modifications during bone development

Research Description: Life is sustained by the complex interplays between many genes. The interaction structure can be reconstructed using gene expression measurements because gene regulatory systems have a defined ordering of pathways that assemble into networks. One hallmark of network dynamics is stability, which allows for cells to maintain their cell types. Henry is studying the gene network stability of human embryonic stem cells by carrying out experiments and developing statistical methods for inferring network structure from experimental data. Ultimately, Henry hopes to build a network that can predict stem cell states to understand self-renewal and pluripotency at the systems level.


Henry is a senior data scientist at Bigeye.