Dr. Rohatgi's laboratory is working to elucidate the biochemical and cell biological principles that govern signaling pathways that sit at the intersection between developmental biology and cancer. Their toolkit combines bulk biochemical techniques, such as cell-free reconstitution, with microscopy using novel optical probes to study the dynamics of signal propagation in cells. They strive to develop novel strategies for the manipulation of these pathways for cancer therapies and applications in regenerative medicine.