Dr. Kenneth Yamada's group's overall research goals are to discover novel mechanisms and regulators of cell interactions with the extracellular matrix and their roles in craniofacial development and disease pathogenesis. They are focusing on mechanisms by which the extracellular matrix, integrins, Rho family GTPase signaling systems, and the cytoskeleton act in concert to mediate or regulate cell adhesion, migration, invasion, matrix remodeling, and tissue morphogenesis.
The Engelhardt Group develops statistical models and methods for high-dimensional genomic data. In particular, we study human genetic variation and its impact on genomic regulation, including gene expression and splicing, with the goal of identifying mechanisms of human disorders and diseases.
Dr. Tatiana Segura's laboratory is interested designing therapies to treat stroke related disability, which are administered weeks to months after stroke. Their approach is to inject hydrogel biomaterial scaffolds into the stroke lesion that can remove the cytotoxic environment and allow pro-repair mechanisms to evolve. In this talk, Dr. Segura will focus on our efforts to design hyaluronic acid microporous annealed particle (HA-MAP) hydrogels to treat stroke related tissue loss.
In this lecture, we will present our recent work in the field of cryo-ET and in situ structural biology, highlighting technological developments and their potential, and offering a perspective to obtain "anatomical" details at the molecular level from larger cells or tissues - towards a biopsy at the nanoscale.
Dr. Doe and his lab group study the assembly of the nervous system in the fruit fly Drosophila. They are interested in how neuronal diversity is generated, how it is used to establish neuronal circuits, and how circuits generate diverse locomotor behaviors.
Christine Stabell Benn has found in population-based epidemiological studies in one of the world’s poorest countries, Guinea-Bissau, that vaccines not only protect against the target infection, they also affect the susceptibility to other infections.