The Benfey laboratory addresses the question how cells acquire their identities using a combination of genetics, molecular biology and genomics to identify and characterize the genes that regulate formation of the root in the plant model system, Arabidopsis thaliana.
Dr. Wong will discuss how organization of immune ligands impacts immune activation via Toll-Like Receptors, the surprising role played by innate immunity peptides in this organization, and how these effects are at play in inflammation induced by heart disease, necrotic cell death, neutrophil extracellular traps, and autoimmune diseases.
It has long been assumed that local lymph formation is driven primarily by pressure gradients generated by interstitial fluid stress and downstream lymphatic pump function, but Dr. Swartz's lab has found that vesicular transendothelial transport also contributes significantly to lymph formation and is actively regulated by the lymphatic endothelium according to inflammatory stimuli, allowing fine control of the delivery of antigens, cells, and chemokines to the local lymph node.
Dr. Stupp's lecture will demonstrate the use of supramolecular biomaterials in regeneration of the spinal cord, cartilage, bone, muscle, and blood vessels, among others; and will also describe the possibility of using these systems dynamically to turn signals to cells "on and off" reversibly, a direction which may prove useful in the management of stem cells in regenerative medicine.
Dr. Brownell will discuss recent work examining the experiences of women and LGBTQIA students in active learning classrooms, including small group discussions. This work will hopefully help instructors to consider structuring their in-class activities in ways that promote equity, which may require more purposeful attention to alleviating the current differential student experiences with peer discussions.
Optical coherence tomography, an imaging modality based on interferometric detection of backscattered infrared light, was initially demonstrated in 1991. The technical advances as well as the hurdles that underpin the long development timeline of OCT will be discussed and the current clinical status will be reviewed.
Vaccines have produced one of the largest increases in the age of life expectancy in human history. However massive challenges remain, with 17 million deaths per year due to infectious disease – mostly in the developing-world. Professor Kendall will discuss the particular challenges holding back vaccines within the developing world; together with potential solutions under development.
The Jacobs-Wagner group studies the temporal and spatial mechanisms involved in bacterial physiology, with emphasis on chromosome dynamics, cell division, cell cycle regulation, cell morphogenesis and RNA biology. Their primary model organisms are Caulobacter crescentus, Escherichia coli and the Lyme disease pathogen Borrelia burgdorferi.