In this lecture, we will present our recent work in the field of cryo-ET and in situ structural biology, highlighting technological developments and their potential, and offering a perspective to obtain "anatomical" details at the molecular level from larger cells or tissues - towards a biopsy at the nanoscale.
Roger Kornberg
Karl Deisseroth
PJ Utz
Shaul Druckmann
Calvin Kuo
Brian Kobilka
Carla Shatz
Alfred Spormann
Nirao Shah
Shirit Einav
Marion Buckwalter
Stanley Lei Qi
Manu Prakash
Fan Yang
Theo Palmer
Ching-Pin Chang
RACHEL GREEN, JOHNS HOPKINS UNIVERSITY
Work in the Green lab is centered on the ribosome, and can be roughly divided into four general project areas. The longest-standing research area concerns the interactions of eubacterial ribosomes and release factors. The goal of these projects is to understand the mechanism of action of release factors on the ribosome.
PAUL FRANÇOIS, MCGILL UNIVERSITY
The François lab is interested in the theoretical aspects of evolution, real and simulated. They have developed tools to evolve models of "gene networks" in silico, performing predefined biological functions. They have applied and predicted structure of networks for systems ranging from genetic oscillators, biochemical adaptation to development and immune system.
SALLY HORNE-BADOVINAC, UNIVERSITY OF CHICAGO
The Horne-Badovinac lab uses genetic, cell biological and quantitative live imaging approaches to investigate how organs take on their unique shapes during development. Currently, they seek to understand how collective cell migration and basement membrane remodeling shape the fly egg.
